ACTL6A, Mouse, Clone: 3C4, Abnova™

Catalog No.	Quantity
89-016-034	100 μg

Catalog No. 89-016-034 Supplier Abnova Corporation Supplier No. H00000086M10

Description

Mouse monoclonal antibody raised against a partial recombinant ACTL6A.

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq

Sequence: MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLM

Specifications

• Antigen: ACTL6A
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 3C4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant ACTL6A.
• Formulation: PBS with no preservative; pH 7.4
• Gene: ACTL6A
• Gene Accession No.: NM_177989
• Gene Alias: ACTL6/ARPN-BETA/Arp4/BAF53A/INO80K/MGC5382
• Gene Symbols: ACTL6A
• Host Species: Mouse
• Immunogen: ACTL6A (NP_817126, 1 a.a. ∼ 80 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 86
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ