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activin A receptor, type IIA, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89018808 Shop All Abnova Corporation Products
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89-018-808 50 μL
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Catalog No. 89-018-808 Supplier Abnova Corporation Supplier No. H00000092A01
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Description

Mouse polyclonal antibody raised against a partial recombinant ACVR2A.

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq

Sequence: RSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPK

Specifications

Antigen activin A receptor, type IIA
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant ACVR2A.
Formulation 50% glycerol
Gene ACVR2A
Gene Accession No. NM_001616
Gene Alias ACTRII/ACVR2
Gene Symbols ACVR2A
Host Species Mouse
Immunogen ACVR2A (AAH67418.1, 24 a.a. ∼ 133 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Research Discipline Membrane Receptors
Primary or Secondary Primary
Gene ID (Entrez) 92
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Serum
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