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Description
Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes. [provided by RefSeq
Specifications
Specifications
| Antigen | ACY1 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 4F1-B7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full length recombinant ACY1. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | ACY1 |
| Gene Accession No. | BC000545 |
| Gene Alias | ACY1D/ACYLASE |
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