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ADAM9 Mouse, Unlabeled, Clone: 15, BD

Catalog No. BDB610750 Shop All BD Biosciences Products
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BDB610750 50 μg
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Catalog No. BDB610750 Supplier BD Biosciences Supplier No. 610750

Description

Mouse Monoclonal Antibody

MDC9 (metalloprotease/disintegrin/cysteine-rich protein 9) belongs to a family of cellular disintegrins known as ADAM (A Disintegrin And Metalloprotease domain). The ADAM proteins are involved in cell-cell and cell-matrix adhesion and, possibly, the degradation of the extracellular matrix. All members possess: 1) a prodomain; 2) a metalloprotease-, disintegrin-, and EGF-like region; 3) a cysteine-rich region; 4) a transmembrane domain; and 5) a cytoplasmic domain. In addition to these regions, MDC9 contains two cytoplasmic proline-rich sequences that may bind to the SH3 domains of cytoskeletal or signaling proteins. MDC9 also contains a membrane-bound metalloprotease and disintegrin domain, suggesting multifunctional activity. Immunofluorescence staining demonstrated that MDC9 is located at the plasma membrane. MDC9 human and mouse protein sequence share 82% identity and are ubiquitously expressed.

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen ADAM9
Applications Immunofluorescence, Western Blot
Classification Monoclonal
Clone 15
Concentration 250μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen Human MDC9 aa. 86-227
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Isotype IgG1
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