ADAM9 Mouse, Unlabeled, Clone: 15, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 610750

Catalog No. BDB610750

Description

MDC9 (metalloprotease/disintegrin/cysteine-rich protein 9) belongs to a family of cellular disintegrins known as ADAM (A Disintegrin And Metalloprotease domain). The ADAM proteins are involved in cell-cell and cell-matrix adhesion and, possibly, the degradation of the extracellular matrix. All members possess: 1) a prodomain; 2) a metalloprotease-, disintegrin-, and EGF-like region; 3) a cysteine-rich region; 4) a transmembrane domain; and 5) a cytoplasmic domain. In addition to these regions, MDC9 contains two cytoplasmic proline-rich sequences that may bind to the SH3 domains of cytoskeletal or signaling proteins. MDC9 also contains a membrane-bound metalloprotease and disintegrin domain, suggesting multifunctional activity. Immunofluorescence staining demonstrated that MDC9 is located at the plasma membrane. MDC9 human and mouse protein sequence share 82% identity and are ubiquitously expressed.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

• Antigen: ADAM9
• Classification: Monoclonal
• Concentration: 250μg/mL
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Isotype: IgG1

• Applications: Immunofluorescence, Western Blot
• Clone: 15
• Conjugate: Unconjugated
• Immunogen: Human MDC9 aa. 86-227
• Quantity: 50 μg
• Research Discipline: Cell Biology
• Target Species: Human, Mouse, Rat