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ADAM9 Mouse, Unlabeled, Clone: 15, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610750

Catalog No. BDB610750

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

MDC9 (metalloprotease/disintegrin/cysteine-rich protein 9) belongs to a family of cellular disintegrins known as ADAM (A Disintegrin And Metalloprotease domain). The ADAM proteins are involved in cell-cell and cell-matrix adhesion and, possibly, the degradation of the extracellular matrix. All members possess: 1) a prodomain; 2) a metalloprotease-, disintegrin-, and EGF-like region; 3) a cysteine-rich region; 4) a transmembrane domain; and 5) a cytoplasmic domain. In addition to these regions, MDC9 contains two cytoplasmic proline-rich sequences that may bind to the SH3 domains of cytoskeletal or signaling proteins. MDC9 also contains a membrane-bound metalloprotease and disintegrin domain, suggesting multifunctional activity. Immunofluorescence staining demonstrated that MDC9 is located at the plasma membrane. MDC9 human and mouse protein sequence share 82% identity and are ubiquitously expressed.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

Specifications

ADAM9
15
Unconjugated
Murine
IgG1
RUO
Primary
Human, Murine, Rat
Immunofluorescence, Western Blot
250μg/mL
Affinity Purified
Human MDC9 aa. 86-227
50μg
Cell Biology
Monoclonal
Documents
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