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Invitrogen™ ADAMTS5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA532658
Description
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Marmoset (95%) Panda, Pig (85%) Rat, Bovine (80%).
ADAMTS5, also known as Implantin or Aggrecanase 2, is a member of the larger family of ADAMs (A Disintegrin And Metalloproteinase) metalloproteinases containing thrombospondin (TS) repeats. ADAMTS5 (A Disintegrin And Metalloproteinase with Thrombospondin-5 motif) was first described as ADAMTS5, a protein elevated in mice during the peri-implantion period. At the same time, another group identified Aggrecanase 11, a protein elevated in arthritic synovium. The name was later changed to ADAMTS5. ADAMTS5 is expressed in human and mouse. It has been found in heart, lung, cervix, uterus, ovary, brain, cartilage, and numerous other tissues, as well as chondroblastoma cell lines.
Specifications
ADAMTS5 | |
Polyclonal | |
Unconjugated | |
ADAMTS5 | |
9530092O11Rik; a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 11; A disintegrin and metalloproteinase with thrombospondin motifs 5; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2); ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 5; ADAM metallopeptidase with thrombospondin type 1 motif, 5; ADAMs; ADAM-TS 11; ADAM-TS 5; ADAMTS family member; ADAMTS1; ADAMTS11; ADAMTS-11; ADAMTS5; ADAM-TS5; ADAMTS-5; ADMP2; ADMP-2; Aggrecanase 2; Aggrecanase-2; AI481094; ASMP-2; Implantin; metalloendopeptidases | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
11096 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 0.1% sodium azide | |
Q9UNA0 | |
ADAMTS5 | |
Synthetic 20 amino acid peptide from N-terminus of human ADAMTS5. | |
50 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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