AGT, Mouse, Clone: 1A10, Abnova™

Catalog No.	Quantity
89-016-072	100 μg

Catalog No. 89-016-072 Supplier Abnova Corporation Supplier No. H00000183M01

Description

Mouse monoclonal antibody raised against a partial recombinant AGT.

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq

Sequence: TIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA

Specifications

• Antigen: AGT
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1A10
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant AGT.
• Formulation: PBS with no preservative; pH 7.4
• Gene: AGT
• Gene Accession No.: BC011519
• Gene Alias: ANHU/FLJ92595/FLJ97926/SERPINA8
• Gene Symbols: AGT
• Host Species: Mouse
• Immunogen: AGT (AAH11519, 376 a.a. ∼ 485 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 183
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 λ