Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. BDB565265

Aiolos Mouse anti-Mouse, Alexa Fluor 647, Clone: S48-791, BD

Catalog No. BDB565265 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB565265 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. BDB565265 Supplier BD Biosciences Supplier No. 565265
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

The S48-791 monoclonal antibody specifically recognizes the transcription factor, Aiolos, which is encoded by Ikzf3 , IKAROS family zinc finger 3. Aiolos belongs to the Ikaros family of zinc-finger proteins that includes Ikaros and Helios. Aiolos can form homodimers or heterodimers with other Ikaros family members. Aiolos is expressed in committed lymphoid progenitors, thymocytes, and mature types of T and B lymphocytes and NK cells. It is not expressed by hematopoietic stem cells. Aiolos plays an important role in the control of B lymphocyte differentiation and proliferation and is specifically required for the generation of long-lived, high affinity plasma cells in the bone marrow. Aiolos is involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. Aiolos is also expressed by Th17 cells and reportedly promotes their differentiation by downregulating IL-2 expression.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Aiolos
Applications Flow Cytometry
Classification Monoclonal
Clone S48-791
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description Ikzf3; IKAROS family zinc finger 3; Zfpn1a3; Znfn1a3
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Mouse
Immunogen Human Aiolos Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.