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Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | AKAP12, |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3C3 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant AKAP12. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | AKAP12 |
| Gene Accession No. | NM_005100 |
| Gene Alias | AKAP250/DKFZp686M0430/DKFZp686O0331/FLJ20945/FLJ97621 |
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