AKR1C2, Mouse, Clone: 3C11, Abnova
Mouse monoclonal antibody raised against a partial recombinant AKR1C2.
Manufacturer: Abnova Corporation H00001646M03A
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeqSequence: EEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPVSDEY
|aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)|
|AKR1C2 (AAH63574, 224 a.a. ∽324 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26kDa|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|In ascites fluid|
|AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2|
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