Learn More
Description
Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).[supplied by OMIM
Specifications
Specifications
| Antigen | ALAS1 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3G10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant ALAS1. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | ALAS1 |
| Gene Accession No. | NM_000688 |
| Gene Alias | ALAS/ALAS3/ALASH/MIG4 |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.