MilliporeSigma™ anti-ALDH2 Clone: 100000,

Catalog No.	Quantity	Conjugate
ST1533100UG	100 μg	Unconjugated

Catalog No. ST1533100UG Supplier MilliporeSigma™ Supplier No. ST1533100UG

Description

Mouse Monoclonal Antibody

Specifically detects ALDH2 Clone: 100000 in Human samples, and it is validated for ELISA, Immuno Blotting

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while ∽50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low K_m for acetaldehydes, and is localized in mitochondrial matrix.

Specifications

• Antigen: ALDH2
• Applications: ELISA, Immunoblot, Immunoblot
• Classification: Monoclonal
• Clone: 100000
• Conjugate: Unconjugated
• Formulation: In PBS, pH 7.2.
• Host Species: Mouse
• Immunogen: A recombinant polypeptide corresponding to amino acids 408-518 of human ALDH2, expressed as a GST fusion protein
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽50kDa ALDH2 protein in MCF7 cells.
• Target Species: Human
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG2a

For Research Use Only