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aldehyde dehydrogenase 2 family (mitochondrial), Mouse, Clone: 2A7, Abnova™

Catalog No. 89000513 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-000-513 100 μg
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Catalog No. 89-000-513 Supplier Abnova Corporation Supplier No. H00000217M09
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Description

Mouse monoclonal antibody raised against a partial recombinant ALDH2.

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq

Sequence: DGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS

Specifications

Antigen aldehyde dehydrogenase 2 family (mitochondrial)
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2A7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant ALDH2.
Formulation PBS with no preservative; pH 7.4
Gene ALDH2
Gene Accession No. BC002967
Gene Alias ALDH-E2/ALDHI/ALDM/MGC1806
Gene Symbols ALDH2
Host Species Mouse
Immunogen ALDH2 (AAH02967, 408 a.a. ∼ 517 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 217
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG2a κ
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