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Description
This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein. [provided by RefSeq
Specifications
Specifications
| Antigen | ALDOA |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 2E6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant ALDOA. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | ALDOA |
| Gene Accession No. | BC010660 |
| Gene Alias | ALDA/MGC10942/MGC17716/MGC17767 |
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