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MilliporeSigma™ anti-alpha-Epithelial Cell Sodium Channel (20-42), Polyclonal

Catalog No. 324870100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
32-487-0100UG 100 μg Unconjugated
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Catalog No. 32-487-0100UG Supplier MilliporeSigma™ Supplier No. 324870100UG
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Description

Rabbit Polyclonal Antibody

Specifically detects α-Epithelial Cell Sodium Channel (20-42) Clone: in Human, Rat samples, and it is validated for Immunoprecipitation

Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. ENaC in the kidney, lung, and colon plays a role in trans-epithelial Na+ and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is believed to be regulated through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel.
TRUSTED_SUSTAINABILITY

Specifications

Antigen α-Epithelial Cell Sodium Channel (20-42)
Applications Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
Formulation In PBS, 1mg/mL BSA.
Host Species Rabbit
Immunogen a synthetic peptide [LMKGNKREEQGLGPEPAAPQQPT(C)] corresponding to amino acids 20-42 of human α-epithelial cell sodium channel (α-ENaC), conjugated to carrier protein
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽97kDa glycosylatedα-ENaC protein.
Target Species Human, Rat
Content And Storage −20°C
Form Purified
Isotype IgG
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For Research Use Only

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