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Annexin I Mouse, Unlabeled, Clone: 29, BD

Catalog No. BDB610067 Shop All BD Biosciences Products
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Mouse Monoclonal Antibody

Annexin I, also known as lipocortin-1 or calpactin II, is part of a calcium-dependent phospholipid-binding protein family. Members share a common core domain, but each has a unique N-terminal tail that imparts its functional specificity. It is believed that phosphorlyation of this region in annexin I regulates its functions. Annexin I has been implicated in regulating phospholipid vesicle aggregation, mediating inflammatory response, and inhibiting the activity of phospholipase A2. Additionally, it has been found that the 10kDa protein S100C influences annexin I's activity by binding to the N-terminal 13 residues of annexin in a manner similar to that of the annexin II/p11 complex.

Host Species: Mouse
Clone: 29
Isotype: IgG1
Species Reactivity: Human
Immunogen: Cow Annexin I aa. 1-346
Formula Weight [Chemical]: 38kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Annexin I
Applications Western Blot
Classification Monoclonal
Clone 29
Concentration 250μg/mL
Conjugate Unconjugated
Description Lipocortin-1; Calpactin II
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Cow Annexin I aa. 1-346
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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