Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Annexin II Mouse, Unlabeled, Clone: 5, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 610069

 View more versions of this product

Catalog No. BDB610069


Only null left
Add to Cart

Description

Description

Annexin II (p36), originally discovered as a substrate for the src oncogene, is one of the most studied members of the annexin family of calcium-dependent phospholipid-binding proteins. It exists in cells as either a monomer or a heterotetramer complexed with p11, an S100-related protein. In vitro, it has been found that unphosphorylated annexin II is capable of causing aggregation of chromaffin granules, and, upon phosphorylation, induces fusion of the granules membranes. A similiar phenomenon may occur in the final steps of exocytosis after cytoplasmic annexin translocates to the subplasmalemmal region and is phosphorylated by protein kinase C. However, other studies refute annexin II's involvement in exocytosis, and a conclusive role for annexin II in membrane trafficking remains debated.

Host Species: Mouse
Clone: 5
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Annexin II aa. 123-328
Formula Weight [Chemical]: 36kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Annexin II
Monoclonal
250μg/mL
Lipocortin II, Calpactin I
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
5
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Human Annexin II aa. 123-328
150 μg
Cell Biology
Canine, Chicken, Human, Mouse, Rat
IgG1
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.

For Research Use Only.