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Annexin II Light Chain Mouse, Unlabeled, Clone: 148, BD

Catalog No. BDB610071 Shop All BD Biosciences Products
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BDB610070 50 μg
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Catalog No. BDB610071 Supplier BD Biosciences Supplier No. 610071
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Description

Mouse Monoclonal Antibody

Annexin II often exists as a heterotetramer complexed with an 11kDa light chain. This p11 subunit is related to the S100 family of calcium-binding proteins but mutations have rendered it unable to bind calcium. The p11 protein binds to the amino terminus of the annexin II monomer, but not to other annexins. It may regulate the function of annexin II, as the tetrameric form seems to have a higher calcium and phospholipid-binding affinity than the monomeric annexin II. In the cell, p11 has been localized to the cytoplasmic face of the plasma membrane where the annexin II tetramer is known to exist.

Host Species: Mouse
Clone: 148
Isotype: IgG1
Species Reactivity: Human
Immunogen: Cow Annexin II Light Chain aa. 1-97
Formula Weight [Chemical]: 11kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Annexin II Light Chain
Applications Western Blot
Classification Monoclonal
Clone 148
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Cow Annexin II Light Chain aa. 1-97
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Chicken, Human
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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