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Anti-Desmin Mouse, Unlabeled, Clone: RD301, BD

Catalog No. BDB550626 Shop All BD Biosciences Products
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BDB550626 50 μg
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Catalog No. BDB550626 Supplier BD Biosciences Supplier No. 550626

Description

Mouse Monoclonal Antibody

Intermediate filaments (IF) are a subset of cytoskeletal proteins which function to give overall structural integrity to the plasma membrane as well as organize cells into specific tissues. IF proteins can be divided into six major types based upon the similarity in sequence. Desmin belongs to the type III category of IF proteins which are predominantly expressed in muscle cells including cardiac, skeletal and smooth muscle. Furthermore, the expression of desmin is regulated in a stage and tissue-specific manner, since it is induced during terminal differentiation of skeletal muscle cells. In skeletal cardiac muscle cells, desmin is localized in the Z-disk region and at the intercalated disk and acts to stabilize sarcomeres in stimulated muscle. Desmin migrates in SDS/PAGE as a 53 kDa protein.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Anti-Desmin
Applications Western Blot
Classification Monoclonal
Clone RD301
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Purified desmin from chicken gizzard
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Chicken, Human, Mouse, Rat
Content And Storage Store undiluted at 4°C
Isotype IgG2b
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For Research Use Only.

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