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AP2 alpha Rabbit anti-Human, Mouse, Ovine, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA125327

Catalog No. PIPA125327


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Description

Description

PA1-25327 detects AP2 alpha from human samples. PA1-25327 is expected to cross react with mouse (94% conserved), rat (94% conserved), chicken (88% conserved), and ovine (94% conserved) due to sequence homology. PA1-25327 has been successfully used in Western blot and immunofluorescence procedures. The PA1-25327 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues S(420) H T D N N A K S S D K E E K H R K(437) of human AP2 alpha. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5 ft.-GCCNNNGGC-3 ft.. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

AP2 alpha
Polyclonal
Unconjugated
TFAP2A
Liquid
TFAP2A
Synthetic peptide, conjugated to KLH, corresponding to residues S(420) H T D N N A K S S D K E E K H R K(437) of human AP2 alpha.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Ovine, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
0.9 mg/mL
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4
P05549, P34056, Q9N0N3, P58197
AP-2, AP-2alpha, AP2TF, BOFS, FLJ51761, TFAP2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
21418, 306862, 443109, 7020
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