APC, Mouse, Clone: 3E2, Abnova™

Catalog No.	Quantity
89-016-163	100 μg

Catalog No. 89-016-163 Supplier Abnova Corporation Supplier No. H00000324M01

Description

Mouse monoclonal antibody raised against a partial recombinant APC.

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq

Sequence: NPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV

Specifications

• Antigen: APC
• Applications: ELISA, Immunofluorescence, In situ PLA, Western Blot
• Classification: Monoclonal
• Clone: 3E2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant APC.
• Formulation: PBS with no preservative; pH 7.4
• Gene: APC
• Gene Accession No.: NM_000038
• Gene Alias: BTPS2/DP2/DP2.5/DP3/GS
• Gene Symbols: APC
• Host Species: Mouse
• Immunogen: APC (NP_000029, 2744 a.a. ∼ 2843 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 324
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ