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MilliporeSigma™ anti-APC Clone: CC-1,

Catalog No. OP80100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
OP80100UG 100 μg Unconjugated
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Description

Mouse Monoclonal Antibody

Specifically detects APC Clone: CC-1 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunofluorescence

Germ line mutations in the APC gene are responsible for familial adenomatous polyposis and somatic mutations contribute to sporadic colorectal cancer. The 312kDa APC protein is expressed in all tissues and localized to the cytoskeletal architecture in an insoluble complex with β-catenin. The APC (Ab-7) mouse monoclonal antibody clone CC-1 decorates oligodendrocyte cell bodies, purkinje cells, astrocytes, and optic nerve cell bodies of formalin-fixed, paraffin-embedded, or fresh frozen sections from human, mouse, and rat brain. Dectection of APC (Ab-7) can be perfomed using immunofluorescence or immunohistochemistry techniques.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC
Applications Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone CC-1
Conjugate Unconjugated
Formulation In 50mM sodium phosphate buffer, 0.2% gelatin.
Host Species Mouse
Immunogen a recombinant protein consisting of amino acids 1-226 of APC
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes APC in oligodendrocytes and astrocytes. Antibody Target Gene Symbol: APC Target Synonym: AI047805, Apc7, AU020952, AW124434, BTPS2, DP2, DP2.5, DP3, Familial adenomatous polyposis, FAP, GS, Min, RATAPC Entrez Gene Name: adenomatous polyposis coli
Target Species Human, Mouse, Rat
Content And Storage 2°C to 8°C
Form Purified
Isotype IgG2b
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