APH1 Rabbit anti-Bovine, Canine, Equine, Human, Marsupial, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523466
DescriptionGamma-secretase subunit APH1A (APH-1A) is a Notch signaling pathway protein and belongs to the APH-1 family. It is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It is likely a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. It is widely expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.
|Synthetic peptide (96 KADEGLASLSEDGRSPIS 113) of APH1A protein.|
|Bovine, Canine, Equine, Human, Marsupial, Non-human Primate, Rat|
|PBS with 0.05% BSA and 0.05% sodium azide|
|RP4-790G17.3, 6530402N02Rik, APH-1, APH-1A, CGI-78, aph-1alpha, gamma-secretase subunit APH-1A, presenilin-stabilization factor|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100054581, 100855839, 365872, 51107, 539247|
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