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APH1 Rabbit anti-Bovine, Canine, Equine, Human, Marsupial, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523466

Catalog No. PIPA523466


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Description

Description

Gamma-secretase subunit APH1A (APH-1A) is a Notch signaling pathway protein and belongs to the APH-1 family. It is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It is likely a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. It is widely expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.
Specifications

Specifications

APH1
Polyclonal
Unconjugated
APH1A
Liquid
APH1A
Synthetic peptide (96 KADEGLASLSEDGRSPIS 113) of APH1A protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Canine, Equine, Human, Marsupial, Non-human Primate, Rat
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q96BI3
RP4-790G17.3, 6530402N02Rik, APH-1, APH-1A, CGI-78, aph-1alpha, gamma-secretase subunit APH-1A, presenilin-stabilization factor
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100054581, 100855839, 365872, 51107, 539247
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