APOC4, Mouse, Clone: 2C12, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant APP.

Manufacturer: Abnova Corporation H00000351M01

Catalog No. 89-016-178

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    Specifications

    Antigen APOC4
    Applications Enzyme Linked Immunosorbent Assay,Immunoprecipitation,Sandwich ELISA,Western Blotting
    Clone 3D10
    Conjugate Unlabeled
    Cross Reactivity Human
    Description amyloid beta (A4) precursor protein
    Format Liquid
    Formulation In 1X PBS, pH 7.4
    Gene APP
    Gene Accession No. BC004369
    Gene Alias AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2
    Gene Symbols APP
    Host Species Mouse
    Immunogen APOC4 (AAH20723, 27 a.a. ∽128 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26kDa.
    Isotype IgG2a, κ
    Quantity 100μg
    Regulatory Status RUO
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal
    Gene ID (Entrez) 351

    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq

    Sequence: EVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREKWYKEVHSGQARWLML

  • Description & Specifications

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