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APOE, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89200280 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-200-280 1 mg x up to 3 Abs
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Catalog No. 89-200-280 Supplier Abnova Corporation Supplier No. H00000348K

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human APOE peptide using ARM Technology.

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen APOE
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description apolipoprotein E
Formulation In 1X PBS, pH 7.4
Gene APOE
Gene Accession No. APOE
Gene Alias AD2, LPG, MGC1571, apoprotein
Gene Symbols APOE
Host Species Rabbit
Immunogen A synthetic peptide of human APOE
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 348
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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