MilliporeSigma™ Apolipoprotein A-I, Mouse, Unlabeled, Clone: A/13,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MAB011A/13

Catalog No. MAB011A13

Description

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Specifications

• Antigen: Apolipoprotein A-I
• Classification: Monoclonal
• Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
• Formulation: IgG fraction purified from mouse ascites by DEAE column chromatography. In 0.015M potassium phosphate buffer with 0.15M NaCl, 0.1% Sodium Azide, pH 7.2.
• Gene Accession No.: P02647
• Host Species: Mouse
• Quantity: 250 μg
• Research Discipline: Lipid Metabolism and Weight Regulation
• Gene ID (Entrez): NM_000039.1
• Target Species: Human
• Form: Purified

• Applications: Radioimmune Assays (RIA)
• Clone: A/13
• Conjugate: Unconjugated
• Gene: APOA1, ApoA-I, preproapolipoprotein, amyloidosis, MGC117399, Apo-AI
• Gene Symbols: APOA1, ApoA-I, preproapolipoprotein, amyloidosis, MGC117399, Apo-AI
• Immunogen: Purified human plasma Apo A-I.
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Apolipoprotein A-I. No cross reactivity to Apo A-II or Apo B. Affinity Constant: 8 x 10⁹L/mol
• Content And Storage: Maintain at -20°C in undiluted aliquots for up to 12 months. Do not store below -20°C or in dry ice as precipitation may occur. Avoid repeated freeze/thaw cycles.
• Isotype: IgG1

For Research Use Only. Not for use in diagnostic procedures.