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arrestin, beta 2, Mouse, Clone: 4D2, Abnova™

Mouse monoclonal antibody raised against a partial recombinant ARRB2.

Supplier:  Abnova Corporation H00000409M06

Catalog No. 89-000-530


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Description

Description

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq

Sequence: NLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC
Specifications

Specifications

arrestin, beta 2
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC007427
ARRB2
ARRB2 (AAH07427, 300 a.a. ∼ 409 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Yes
409
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG2a κ
ELISA, Immunofluorescence, Western Blot
4D2
Mouse monoclonal antibody raised against a partial recombinant ARRB2.
ARRB2
ARB2/ARR2/BARR2/DKFZp686L0365
Mouse
Affinity Purified
RUO
Primary
Human
Antibody
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