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Description
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
Specifications
Specifications
| Antigen | activating transcription factor 2 |
| Applications | ELISA, In situ PLA, Western Blot |
| Classification | Monoclonal |
| Clone | 3A3 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full length recombinant ATF2. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | ATF2 |
| Gene Accession No. | NM_001880 |
| Gene Alias | CRE-BP1/CREB2/HB16/MGC111558/TREB7 |
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