activating transcription factor 4 (tax-responsive enhancer element B67), Mouse, Clone: 2B3, Abnova™ Available on GSA/VA Contract for Federal Government customers only.

Mouse monoclonal antibody raised against a partial recombinant ATF4.

Manufacturer: Abnova Corporation H00000468M01

Catalog No. 89-014-058

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    Formulation In 1X PBS, pH 7.4
    Gene ATF4
    Gene Accession No. NM_001675
    Gene Alias CREB-2, CREB2, TAXREB67, TXREB
    Gene Symbols ATF4
    Applications Enzyme Linked Immunosorbent Assay,Sandwich ELISA,Western Blotting
    Species Reactivity Human, Mouse
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Gene ID (Entrez) 468
    Description activating transcription factor 4 (tax-responsive enhancer element B67)
    Isotype IgG1
    Quantity 100μg
    Clone 2B3
    Antigen activating transcription factor 4 (tax-responsive enhancer element B67)
    Format Affinity Purified
    Host Species Mouse
    Immunogen ATF4 (NP_001666, 171 a.a. ∽271 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Regulatory Status RUO
    Research Discipline Transcription Regulation
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal
    Conjugate Unlabeled
    Cross Reactivity Human,Mouse
    Purification Method Protein A column

    This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. [provided by RefSeq


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