Human/Mouse BACE-1 Ectodomain Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 6 publications

Catalog Number	Mfr. No.	Quantity
MAB931SP	R&D Systems MAB931SP	25 μg
MAB931100	R&D Systems MAB931100	100 μg
MAB931500	R&D Systems MAB931500	500 μg

Description

BACE-1 Monoclonal specifically detects BACE-1 in Human, Mouse samples. It is validated for Western Blot, Immunohistochemistry, Intracellular Staining by Flow Cytometry, CyTOF-ready.

Specifications

• Antigen: BACE-1
• Concentration: LYOPH
• Applications: Western Blot, Immunohistochemistry, Flow Cytometry, CyTOF
• Conjugate: Unconjugated
• Regulatory Status: RUO
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: APP beta-secretase, ASP2, Aspartyl protease 2, BACE1, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2
• Gene Symbols: BACE1
• Isotype: IgG1
• Purification Method: Protein A or G purified from hybridoma culture supernatant
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

• Clone: 137612
• Dilution: Western Blot 2 ug/mL, Immunohistochemistry 8-25 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human, Mouse
• Gene Accession No.: P56817
• Gene ID (Entrez): 23621
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human BACE-1 Thr22-Tyr460 Accession # P56817
• Primary or Secondary: Primary
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Test Specificity: Detects human and mouse BACE-1 in direct ELISAs and human BACE-1 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BACE-2, recombinant mouse (rm) BACE-2, rhADAM8, rmADAM9, rmADAM10, rhADAM15, or rhTACE is observed.

For Research Use Only