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BAG3, Rabbit, Monoclonal Antibody, Abnova™
Rabbit monoclonal antibody raised against a human BAG3 peptide using ARM Technology.
Supplier: Abnova Corporation H00009531K
Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.
Description
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
BAG3 | |
Monoclonal | |
Unconjugated | |
In 1X PBS, pH 7.4 | |
BAG3 | |
BAG3 | |
A synthetic peptide of human BAG3 | |
RUO | |
9531 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
IgG |
ELISA, Western Blot | |
1mg | |
BCL2-associated athanogene 3 | |
BAG3 | |
BAG-3, BIS, CAIR-1, MGC104307 | |
Rabbit | |
1 mg x up to 3 Abs | |
Primary | |
Human | |
Liquid |
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