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Description
Includes
Up to three rabbit IgG clones of 1mg each will be delivered to customer.
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms
Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
Specifications
| Antigen | BAIAP2 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1mg |
| Conjugate | Unconjugated |
| Description | BAI1-associated protein 2 |
| Formulation | In 1X PBS, pH 7.4 |
| Gene | BAIAP2 |
| Gene Accession No. | BAIAP2 |
| Gene Alias | BAP2, IRSP53 |
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