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basic FGF Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

$232.00 - $427.00

Specifications

Antigen basic FGF
Isotype IgG2a
Immunogen Human bFGF aa. 1-155
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610072
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BD Biosciences
610072
50μg
Each for $232.00
Add to cart
 
BDB610073
View Documents
BD Biosciences
610073
150μg
Each for $427.00
Add to cart
 
Description

Description

Basic Fibroblast Growth Factor (bFGF) is a family member of the cell-differentiating and growth promoting factors. Basic FGF exists as multiple isoforms ranging from 18-24kDa that are derived from a single mRNA species under unique translational conditions. The 18kDa isoform is primarily cytosolic, but is also secreted and may form reservoirs of bFGF in the extracellular matrix. In contrast, the larger isoforms are predominantly nuclear. At the cellular level, bFGF is a potent mitogen and promotes cell survival by inhibiting apoptosis. At the tissue level, it is involved in wound repair and induces angiogenesis. In addition, bFGF is a significant target in cancer research because it is over-expressed in some cancers and may enhance a tumor's metastatic potential.

Host Species: Mouse
Clone: 6
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Human bFGF aa. 1-155
Formula Weight [Chemical]: 18-24kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

basic FGF
Human bFGF aa. 1-155
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG2a
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
6
250μg/mL
SDS
Product Certifications

For Research Use Only.

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