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  6. anti-BCL-2α Ab-4, Clone: 10C4, Epredia™ LabVision

anti-BCL-2α Ab-4, Clone: 10C4, Epredia™ LabVision

Catalog No. MS598B0 Shop All Epredia Products
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MS598B1 500 μL
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Catalog No. MS598B0 Supplier Epredia Supplier No. MS598B0

Description

Mouse Monoclonal Antibody

Expression of Bcl-2α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2α protein, whereas the normal or hyperplastic germinal centers are negative.

Host Species: Mouse
Clone: 10C4
Isotype: IgG1
Cross Reactivity: Mouse and Rat. Does not react with human. Others-not tested.
Epitope: aa 61-76
Immunogen: A Synthetic peptide, aa 61-76 (Cys-VHREMAARTSPLRPLV), of Mouse bcl-2 protein.
Molecular Weight: 25-26kDa
Positive Control: MAD109 cells.
Cellular Localization: Cytoplasm

Ab-4 is particularly designed for research on mouse and rat bcl-2alpha protein. It does not react with human bcl-2alpha protein.

Immunofluorescence, Immunoprecipitation, Western Blotting

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

Antigen BCL-2α Ab-4
Classification Monoclonal
Concentration 200μg/mL
Host Species Mouse
Immunogen A Synthetic peptide, aa 61-76 (Cys-VHREMAARTSPLRPLV), of Mouse bcl-2 protein.
Quantity 100 μL
Primary or Secondary Primary
Target Species Mouse, Rat
Isotype IgG1
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