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Bcl-X set Mouse, Unlabeled, Clone: 2H12, BD

Catalog No. BDB551022 Shop All BD Biosciences Products
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150 μg
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BDB551022 150 μg
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Catalog No. BDB551022 Supplier BD Biosciences Supplier No. 551022
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Description

Mouse Monoclonal Antibody

Members of the Bcl-2 family play a major role in regulating the response of cells to a wide variety of apoptotic signals. Some Bcl-2 family members like Bcl-2, block apoptosis, whereas others promote apoptosis and inhibit Bcl-2 activity. Bcl-x is a Bcl-2 homologue that has two isoforms, resulting from alternative splicing. Bcl-xL (long) is a 241 amino acid protein (25-29 kDa) that is 47% homologous to Bcl-2 on the amino acid level. Bcl-xS (short) is a 178 amino acid protein (∼ 19.5 kDa) lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 protein family. Bcl-xL blocks cell death, whereas Bcl-xS inhibits Bcl-2 and promotes cell death.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-X set
Applications Western Blot
Classification Monoclonal
Clone 2H12
Conjugate Unconjugated
Host Species Mouse
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at -20°C.
Isotype IgG2a
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For Research Use Only.

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