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  6. Bcl-X Mouse, Unlabeled, Clone: 4, BD

Bcl-X Mouse, Unlabeled, Clone: 4, BD

Catalog No. BDB610210 Shop All BD Biosciences Products
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150 μg
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BDB610210 150 μg
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Catalog No. BDB610210 Supplier BD Biosciences Supplier No. 610210

Description

Mouse Monoclonal Antibody

Bcl-x is related to the Bcl-2 protein and can function independently of Bcl-2 in regulating apoptosis (programmed cell death). The bcl-x transcript is found in a number of tissues, with the highest levels in the lymphoid and central nervous systems. Two distinct cDNA species, bcl-xL and bcl-xS, have been observed and appear to arise from alternate 5′ splice sites located within the first coding exon of the bcl-x gene. Bcl-xL is composed of 233 amino acids and is similar in size and structure to Bcl-2. Bcl-xS lacks 63 amino acids corresponding to the region of Bcl-xL with the highest degree of homology to Bcl-2. Like Bcl-2, Bcl-xL has been reported to inhibit cell death upon growth factor withdrawal in an IL-3-dependent cell line. However, Bcl-xS inhibits the ability of Bcl-2 to enhance cell survival in the absence of growth factors.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Bcl-X
Applications Western Blot
Classification Monoclonal
Clone 4
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 150 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Chicken, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2b
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For Research Use Only.

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