Livin Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA513119
DescriptionBIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.
|PBS with 0.09% sodium azide|
|Baculoviral IAP repeat-containing protein 7; Kidney inhibitor of apoptosis protein; KIAP; Melanoma inhibitor of apoptosis protein; ML-IAP; Livin; RING finger protein 50; KIAP; LIVIN; MLIAP; RNF50|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human BIRC7|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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