Livin Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA513119

Catalog No. PIPA513119

Description

BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

Specifications

• Antigen: Livin
• Classification: Polyclonal
• Gene: BIRC7
• Gene Alias: Baculoviral IAP repeat-containing protein 7; Kidney inhibitor of apoptosis protein; KIAP; Melanoma inhibitor of apoptosis protein; ML-IAP; Livin; RING finger protein 50; KIAP; LIVIN; MLIAP; RNF50
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 79444
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q96CA5
• Gene Symbols: BIRC7
• Immunogen: KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human BIRC7
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG