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Description
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq]
Specifications
Specifications
| Antigen | BLM |
| Applications | ELISA, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 1E4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant BLM. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | BLM |
| Gene Accession No. | NM_000057 |
| Gene Alias | BS/MGC126616/MGC131618/MGC131620/RECQ2/RECQL2/RECQL3 |
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