BLNK (pY84) Mouse, Alexa Fluor 488, Clone: J117-1278, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 558444

Catalog No. BDB558444

Description

B cell activation is initiated by crosslinking the B cell receptor, which leads to activation of non-receptor protein tyrosine kinases (PTK), including Btk, Syk, and three Src kinases, Fyn, Lyn, and Blk. Activated PTKs then phosphorylate multiple cellular proteins involved in B lymphocyte signaling. Syk is responsible for the tyrosine phosphorylation of B cell l i g 2, leading to the activation of downstream signaling pathways.

The J117-1278 monoclonal antibody recognizes the phosphorylated Y84 of BLNK.

Specifications

• Antigen: BLNK (pY84)
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: J117-1278
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Phosphorylated Human BLNK Peptide
• Quantity: 50 Tests
• Research Discipline: Cell Biology
• Target Species: Human, Mouse
• Isotype: IgG2b κ