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c-Jun (pS63) Mouse, Unlabeled, Clone: 2/C-JUN (PS63), BD

Catalog No. BDB558036 Shop All BD Biosciences Products
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Catalog No. BDB558036 Supplier BD Biosciences Supplier No. 558036
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Description

Mouse Monoclonal Antibody

The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the SV40 virus and the human metallothionein IIA gene. AP-1 is composed of protein products of two different gene families: jun and fos. The AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins. The transcriptional activity of Jun is enhanced by phosphorylation of serines 63 (S63) and 73 in its activation domain. Phosphorylation at both sites is necessary for stimulating the activating function of Jun. Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity. The 2/c-Jun/(S63) monoclonal antibody recognizes the phosphorylated S63 of c-Jun.

Host Species: Mouse
Clone: 2
Isotype: IgG1
Species Reactivity: Human

Immunohistochemistry (Formalin-Antigen Retrieval Required), Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen c-Jun (pS63)
Applications Western Blot
Classification Monoclonal
Clone 2/C-JUN (PS63)
Concentration 0.25mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Phosphorylated Human c-Jun
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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