MilliporeSigma™ anti-c-Myc Clone: 90000000000,

Catalog No.	Quantity	Conjugate
OP107100UG	100 μg	Unconjugated

Catalog No. OP107100UG Supplier MilliporeSigma™ Supplier No. OP107100UG

Description

Mouse Monoclonal Antibody

Specifically detects c-Myc Clone: 90000000000 in Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Immuno Blotting

The v-myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans the family consists of five genes: c-myc, N-myc, R-myc, L-myc, and B-myc. Amplification of the c-myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-myc gene has been found amplified in neuroblastomas, small cell lung carcinomas and Wilms tumors. L-myc is amplified in small cell lung cancer. Immunological studies have shown that the human c-myc gene gives rise to at least two nuclear phosphoproteins of ∽64kDa and ∽67kDa that exhibit relatively short (30 min) half lives in vivo and exhibit DNA binding properties in vitro.

Specifications

• Antigen: c-Myc
• Applications: Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
• Classification: Monoclonal
• Clone: 90000000000
• Conjugate: Unconjugated
• Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin.
• Host Species: Mouse
• Immunogen: a synthetic peptide (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) corresponding to amino acids 408-439 of human c-Myc
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽60-67kDa c-Myc protein in HL60 cells and lung carcinoma tissue.
• Target Species: Human, Mouse, Rat
• Content And Storage: 2°C to 8°C
• Form: Liquid
• Isotype: IgG1

For Research Use Only