centromere protein M, Mouse, Clone: 4C12-2C8, Abnova™

Catalog No.	Quantity
89-014-334	100 μg

Catalog No. 89-014-334 Supplier Abnova Corporation Supplier No. H00079019M01

Description

Mouse monoclonal antibody raised against a full-length recombinant C22orf18.

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM

Sequence: MSVLRPLDKLPGLNTATILLVGTEDALLQQLADSMLKEDCASELKVHLAKSLPLPSSVNRPRIDLIVFVVNLHSKYSLQNTEESLRHVDASFFLGKVCFLATGAGRESHCSIHRHTVVKLAHTYQSPLLYCDLEVEGFRATMAQRLVRVLQICAGHVPGVSALNLLSLLRSSEGPSLEDL

Specifications

• Antigen: centromere protein M
• Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 4C12-2C8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant C22orf18.
• Formulation: PBS with no preservative; pH 7.4
• Gene: CENPM
• Gene Accession No.: BC000705
• Gene Alias: C22orf18/CENP-M/MGC861/PANE1/bK250D10.2
• Gene Symbols: CENPM
• Host Species: Mouse
• Immunogen: C22orf18 (AAH00705, 1 a.a. ∼ 180 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 79019
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG1 κ