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Description
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | carbonic anhydrase XII |
| Applications | ELISA, KnockDown, Western Blot |
| Classification | Monoclonal |
| Clone | 1D4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant CA12. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | CA12 |
| Gene Accession No. | NM_206925 |
| Gene Alias | CAXII/FLJ20151/HsT18816 |
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