anti-CA9, MaxPab™ Polyclonal, Abnova

Rabbit Polyclonal

Manufacturer: Abnova Corporation H00000768B01P

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Catalog No. 89-018-882

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    Antigen carbonic anhydrase IX
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Affinity Purified
    Host Species Mouse
    Immunogen CA9 (NP_001207.1, 1 a.a. ∽459 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 50μg
    Regulatory Status RUO
    Research Discipline Endocrine/Metabolism
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal

    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.

    Host Species: Rabbit
    Species Reactivity [for Features Main]: Human
    Immunogen: CA9 (NP_001207.1, 1 a.a. ~ 459 a.a) full-length human protein.

    Detection Antibody, Western Blotting

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