Calnexin Mouse, Unlabeled, Clone: 37, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 610523
Calnexin is a 90kDa integral membrane protein located primarily in the ER. It contains a long N-terminal calcium-binding domain that extends into the lumen of the ER and a short, acidic cytosolic domain. Calnexin associates with several cell surface proteins as they pass through the ER. Since it also forms complexes with other resident ER proteins involved in the Ca2+-dependent retention of proteins, calnexin may act as a chaperone. The amino acid sequence of calnexin is highly conserved among species and is similar in sequence to calreticulin, another Ca2+-binding protein found in the ER. Neither calnexin nor calreticulin contain the calcium-binding motif, known as the “E-F hand” found in the calmodulin family of proteins.
Host Species: Mouse
Species Reactivity [for Features Main]: Human
Immunogen: Human Calnein aa. 116-301
|Aqueous buffered solution containing BSA|
|Canine, Human, Murine, Rat|
|Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.|
|Store undiluted at -20°C.|
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