Calnexin Mouse, Unlabeled, Clone: 37, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 610523

Catalog No. BDB610523

Description

Calnexin is a 90kDa integral membrane protein located primarily in the ER. It contains a long N-terminal calcium-binding domain that extends into the lumen of the ER and a short, acidic cytosolic domain. Calnexin associates with several cell surface proteins as they pass through the ER. Since it also forms complexes with other resident ER proteins involved in the Ca²⁺-dependent retention of proteins, calnexin may act as a chaperone. The amino acid sequence of calnexin is highly conserved among species and is similar in sequence to calreticulin, another Ca²⁺-binding protein found in the ER. Neither calnexin nor calreticulin contain the calcium-binding motif, known as the “E-F hand” found in the calmodulin family of proteins.

Host Species: Mouse
Clone: 37
Isotype: IgG1
Species Reactivity [for Features Main]: Human
Immunogen: Human Calnein aa. 116-301

Immunofluorescence, Immunoprecipitation

Specifications

• Antigen: Calnexin
• Classification: Monoclonal
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Quantity: 50 μg
• Research Discipline: Cell Biology
• Target Species: Canine, Human, Mouse, Rat
• Isotype: IgG1

• Applications: Western Blot
• Clone: 37
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

For Research Use Only.