Invitrogen™ CaMKI Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1543

Catalog No. PA1543

Description

PA1-543 detects calciμm/calmodulin-dependent kinase I (CaMKI) from rat and mouse brain extract. PA1-543 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~43 kDa protein representing CaMKI from rat and mouse brain extract. PA1-543 immunizing peptide corresponds to amino acid residues 1-18 from human CaMKI protein. PA1-543 immunizing peptide (Cat. # PEP-134) is available for use in neutralization and control experiments.

CAMK1 (CaMK1) is a serine/threonine kinase that is a member of the calcium/calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.

Specifications

• Antigen: CaMKI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMK1
• Gene Alias: AI505105; calcium/calmodulin dependent protein kinase I; calcium/calmodulin-dependent protein kinase I; calcium/calmodulin-dependent protein kinase type 1; CaM kinase I; CaM kinase I alpha; Camk1; CAMK1-PEN; Camki; caM-KI; CaMKIalpha; CaMKI-alpha; D6Ertd263e; G alpha interacting protein; Gaip; MGC120317; MGC120318; regulator of G-protein signalling 19
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171503, 52163, 8536
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: Q14012, Q63450, Q91YS8
• Gene Symbols: CAMK1
• Immunogen: Synthetic Peptide: A(1) V E G P R W K Q A E D I R D I Y D(18).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG