CaM Kinase Kinase Mouse, Unlabeled, Clone: 6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610544

Catalog No. BDB610544

Description

Ca²⁺/Calmodulin (CaM)-dependent kinases are multifunctional kinases involved in a myriad of cellular functions such as neurotransmitter synthesis, long-term potentiation, and formation of spatial learning. A 68kDa CaM Kinase Kinase with homology to the Ca²⁺/CaM-dependent kinases, phosphorylates and activates Ca²⁺/CaM-dependent protein kinases I and IV, but not type II. This phosphorylation occurs on Ser/Thr residues and is Ca²⁺ and CaM dependent. CaM Kinase Kinase is abundant in brain tissue, and is thought to be an upstream regulator in the Ca²⁺/CaM-dependent neural processes.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

• Antigen: CaM Kinase Kinase
• Clone: 6
• Conjugate: Unconjugated
• Format: Affinity Purified
• Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Quantity: 50μg
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Canine, Human, Rat

• Applications: Western Blot
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG_2a
• Regulatory Status: RUO
• Storage Requirements: Store undiluted at -20°C.
• Monoclonal or Polyclonal: Monoclonal

For Research Use Only.