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Description
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Specifications
Specifications
| Antigen | CAMK2A |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1H7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant CAMK2A. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | CAMK2A |
| Gene Accession No. | BC040457 |
| Gene Alias | CAMKA/KIAA0968 |
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