calcium modulating ligand, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-004-039	50 μL

Catalog No. 89-004-039 Supplier Abnova Corporation Supplier No. H00000819A01

Description

Mouse polyclonal antibody raised against a partial recombinant CAMLG.

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq

Sequence: MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQG

Specifications

• Antigen: calcium modulating ligand
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Mouse polyclonal antibody raised against a partial recombinant CAMLG.
• Formulation: 50% glycerol
• Gene: CAMLG
• Gene Accession No.: NM_001745
• Gene Alias: CAML/MGC163197
• Gene Symbols: CAMLG
• Host Species: Mouse
• Immunogen: CAMLG (NP_001736, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag.
• Quantity: 50 μL
• Regulatory Status: RUO
• Whole Molecule: Yes
• Primary or Secondary: Primary
• Gene ID (Entrez): 819
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Serum