MilliporeSigma™ anti-Cannabinoid Receptor CB1 (1-77), Polyclonal

Catalog No.	Quantity	Conjugate
20-955-0100UL	100 μL	Unconjugated

Catalog No. 20-955-0100UL Supplier MilliporeSigma™ Supplier No. 209550100UL

Description

Rabbit Polyclonal Antibody

Specifically detects Cannabinoid Receptor CB₁ (1-77) Clone: in Chicken, Fish, Gerbil, Human, Monkey, Mouse, Rat, Salamander samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin)

Cannabinoids exert their physiological effects through two G-protein coupled receptors, CB₁ and CB₂. Both receptors inhibit adenylyl cyclase and stimulate MAP kinase. CB₁ receptors also modulate ion channels through direct G protein interactions. D-9-tetrahydrocannibinol and related ligands exert their psychoactive effects by inhibiting presynaptic N- and P/Q-type calcium channels. CB₁ receptors are primarily expressed in brain (particularly cortex, striatum, hippocampus and cerebellum), spinal cord, eye, and testis. CB₁ receptors are involved in the modulation of nociception, movement, learning and memory, emotion, and many other neuronal processes.

Specifications

• Antigen: Cannabinoid Receptor CB₁ (1-77)
• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: In PBS, 1mg/mL BSA, 50% glycerol.
• Host Species: Rabbit
• Immunogen: a recombinant protein consisting of the first 77 amino acids of rat CB₁ receptor
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽60kDa CB₁ receptor protein.
• Target Species: Chicken, Fish, Gerbil, Human, Monkey, Mouse, Rat, Salamander
• Content And Storage: −20°C
• Form: Purified
• Isotype: IgG

For Research Use Only