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CHST1 Mouse anti-Human, Clone: 543128, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524243

Catalog No. PIMA524243


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Description

Description

In direct ELISAs, approximately 25-100% cross-reactivity with recombit mouse CHST1 and no cross-reactivity with recombit human CHST2, 3, 4, 5, 6, 7, 10, and 14 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Carbohydrate sulfotransferase 1 (CHST1), also referred to as KSGal6ST or KSST, is a keratan sulfate sulfotransferase. It is predomitly expressed in brain and skeletal muscle and localizes to the trans-Golgi network. CHST1 is responsible for mediating the sulfation of keratan in the cornea, which is important in maintaining corneal transparency. In particular, CHST1 catalyzes the transfer of sulfate groups from 3 ft.-phosphoadenosine 5 ft.-phosphosulfate to position six of internal or terminal galactose residues (preferentially the residues adjacent to sulfated GlcNAc) on growing keratan sulfate chains. CHST1 also contributes to the generation of L-selectin ligands. Mutations in the CHST1 gene may play a role in macular corneal dystrophy (MCD).
Specifications

Specifications

CHST1
Monoclonal
0.2 mg/mL
PBS with 5% trehalose and No Preservative
O43916
Carbohydrate sulfotransferase 1, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1, GST-1, Keratan sulfate Gal-6 sulfotransferase, KS6ST, KSGal6ST, KSST
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
8534
Immunoprecipitation, Neutralization
543128
Unconjugated
CHST1
Lyophilized
CHST1
CHO-derived recombit human Carbohydrate Sulfotransferase 1/CHST1 Arg24-Ser411
Protein A/G
RUO
Antibody
Monoclonal
Human
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